Pharma reactors

Pilot scale reactors are complete reaction systems on free standing movable frames. Industrial design, elevated performing stirring system and industrial type connections guarantee robustness and reliability over time.

Thanks to its compact size and trolley structure, it can be easily transported or placed under a walk-in hood. Suitable for both standard laboratory needs and scale up/research activities. Transparent glass facilitates visual inspections during reaction and guarantees excellent control of reaction temperature and homogeneous liquid stirring.

This multipurpose equipment is ideal for mixing and dissolving corrosive acid or basic liquids and/or solids, for different kinds of reactions (e.g., crystallization reactions, polymerization reactions) and for use in many other applications.

 

Features and options

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Rangeability

  • From 10 L to 100 L
  • Design temperature: – 50°C to + 200°C; larger range available on request
  • Design Pressure: – 1 barg to + 0,5 barg
  • Max vacuum: 5 mbar(a)
  • Compatible with various types of heating media (steam, hot oil and hot water)

Agitator system and mechanical seal

  • Elevated performing stirring system
    • AISI 304 stirring shaft, PTFE coated, with PTFE stirring anchor blade
    • PTFE/glass mechanical seal TM50/26
    • Robust system without breakages caused by turbulences from agitating viscous liquids
    • Easy to clean
  • Wide range of agitation shapes are available on request
  • Optional magnetic drive seal, while other models are available on request

Drive unit

  • Ultra-high torque stirrer, designed for use with remote control
  • Air motor with compact dimensions
  • Electrical gearmotor with manual variator

Bottom valve

  • GMP compact bottom valve
    • Robust and compact design, easy to disassemble and clean
    • The valve completely drains to avoid any residual liquid stagnation
    • With compensation spring

Support frame

  • Structure made of AISI 304 stainless steel
  • Each version is standalone
  • Fitted with wheels for easy handling

Material

  • Material in contact with product: glass, PTFE
  • Vessel: entirely in 3,3 borosilicate glass
  • Lid: 3,3 borosilicate glass
  • Sealing elements: FDA approved PTFE
  • Bottom valve obturator: PTFE
  • Stirring shaft: PTFE
  • Support frame and external parts: AISI 304 stainless steel

Options

  • Equipped with or without thermostatic jacket
  • DN25 connections on the shell
  • ATEX, FDA and GMP compliant
  • Graduated feeding flasks

Accessories

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  • Vacuum skid with vacuum pump with reflux separator
  • Inerting systems provided with oxygen analyser on request
  • Chilling or thermostatic units
  • Condensers and cold traps
  • Cleaning features, with flooding and spray nozzles
  • Distillation kit composed of reflux separator and condenser
  • pH kit with or without display
  • Pt100 temperature probe placed on lid
  • Pt100 temperature probe placed inside bottom valve
    • Product temperature can also be controlled with very low liquid levels
    • Quicker temperature reading when compared to sensor placed on lid
    • No risk of glass sensor breakages due to accidental impacts with solid suspensions
  • Inverter
  • PLC automation systems
  • Electrical cabinet

Applications

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Pharma glass reactors, particularly suitable for use in the pharmaceutical industry, are used for multiple applications across different industries, such as:

  • Base chemical
  • Cosmetics
  • Crop protection
  • Flavours & fragrances
  • Goldsmith
  • Pharmaceutical
  • Precious and technology metals

They can be provided as standalone units or modular turnkey systems to simultaneously satisfy functional needs and efficiency in project costs and execution time.

More about plants

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More about glass lined equipment

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